February 2020 - cypherpunks - lists.cpunks.org

Why could this list be a target for (paid) trolls?
by Georgi Guninski 07 Mar '21

07 Mar '21

Why could this list be a target for (paid) trolls? I hear that this list is target of (paid) trolls and browsing it appears to support this. Why so? I don't see enough "value" in the list for such attack, short of just propaganda playground.

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Chloroquine is "highly effective" at inhibiting reproduction of Novel Coronavirus nCov in cell culture.
by jim bell 31 Jan '21

31 Jan '21

[chloroquine is an old-line drug typically used against malaria] [partial quote follows] https://www.asbmb.org/asbmb-today/science/020620/could-an-old-malaria-drug-… ASBMB Today Science Could an old malaria drug help fight the new coronavirus? Could an old malaria drug help fight the new coronavirus? By John Arnst February 06, 2020 Chloroquine might be getting new life as an antiviral treatment for the novel coronavirus that emerged in Wuhan, China in late 2019 and has infected some 25,000 people in more than 25 countries. For decades, the drug was a front-line treatment and prophylactic for malaria. In a three-page paper published Tuesday in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology write that both chloroquine and the antiviral remdesivir were, individually, “highly effective” at inhibiting replication of the novel coronavirus in cell culture. Their drug screen evaluated five other drugs that were not effective. The authors could not be reached for comment. Though the paper is brief, John Lednicky, a professor at the University of Florida’s Emerging Pathogens Institute, found its results intriguing. “It’s interesting in that it really lacks a lot of details but, nevertheless, if you look at the data as presented, at least in vitro, it seems like chloroquine can be used as an early-stage drug,” he said. “It would be very good if these types of experiments were repeated by more laboratories to see whether the same results occur across the board.” Chloroquine is a synthetic form of quinine, a compound found in the bark of cinchona trees native to Peru and used for centuries to treat malaria. Chloroquine was an essential element of mass drug administration campaigns to combat malaria throughout the second half of the 20th century, and remains one of the World Health Organization’s essential medicines. However, after the malaria parasites Plasmodium falciparum and Plasmodium vivax began exhibiting resistance to the drug in the 1960s and 1980s, respectively, it was replaced by similar antimalarial compounds and combination therapies. Chloroquine is still widely used against the three other species of plasmodium and to treat autoimmune disorders and some cases of amebiasis, an intestinal infection caused by the amoeba Entamoeba histolytica. Chloroquine’s antiviral properties were explored in the mid-1990s against HIV and in the following decade against severe acute respiratory syndrome, or SARS, which is closely related to the novel coronavirus. In 2004, researchers in Belgium found that chloroquine inhibited replication of SARS in cell culture. The following year, however, another team at Utah State University and the Chinese University of Hong Kong evaluated a gamut of compounds against SARS replication in mice infected with the virus, finding that chloroquine was only effective as an anti-inflammatory agent. They recommended that it could be used in combination with compounds that prevent replication. Nevertheless, in 2009, the Belgian group found that lethal infections of human coronavirus OC43, a relative of SARS, could be averted in newborn mice by administering chloroquine through the mother’s milk. [end of partial quote] Also: https://www.nature.com/articles/s41422-020-0282-0 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhengli Shi, Zhihong Hu, Wu Zhong & Gengfu Xiao Cell Research (2020)Cite this article 171k Accesses 1108 Altmetric Metrics details Dear Editor, In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood market in Wuhan.1 As of January 27, 2020, the Chinese authorities reported 2835 confirmed cases in mainland China, including 81 deaths. Additionally, 19 confirmed cases were identified in Hong Kong, Macao and Taiwan, and 39 imported cases were identified in Thailand, Japan, South Korea, United States, Vietnam, Singapore, Nepal, France, Australia and Canada. The pathogen was soon identified as a novel coronavirus (2019-nCoV), which is closely related to sever acute respiratory syndrome CoV (SARS-CoV).2 Currently, there is no specific treatment against the new virus. Therefore, identifying effective antiviral agents to combat the disease is urgently needed. An efficient approach to drug discovery is to test whether the existing antiviral drugs are effective in treating related viral infections. The 2019-nCoV belongs to Betacoronavirus which also contains SARS-CoV and Middle East respiratory syndrome CoV (MERS-CoV). Several drugs, such as ribavirin, interferon, lopinavir-ritonavir, corticosteroids, have been used in patients with SARS or MERS, although the efficacy of some drugs remains controversial.3 In this study, we evaluated the antiviral efficiency of five FAD-approved drugs including ribavirin, penciclovir, nitazoxanide, nafamostat, chloroquine and two well-known broad-spectrum antiviral drugs remdesivir (GS-5734) and favipiravir (T-705) against a clinical isolate of 2019-nCoV in vitro. Standard assays were carried out to measure the effects of these compounds on the cytotoxicity, virus yield and infection rates of 2019-nCoVs. Firstly, the cytotoxicity of the candidate compounds in Vero E6 cells (ATCC-1586) was determined by the CCK8 assay. Then, Vero E6 cells were infected with nCoV-2019BetaCoV/Wuhan/WIV04/20192 at a multiplicity of infection (MOI) of 0.05 in the presence of varying concentrations of the test drugs. DMSO was used in the controls. Efficacies were evaluated by quantification of viral copy numbers in the cell supernatant via quantitative real-time RT-PCR (qRT-PCR) and confirmed with visualization of virus nucleoprotein (NP) expression through immunofluorescence microscopy at 48 h post infection (p.i.) (cytopathic effect was not obvious at this time point of infection). Among the seven tested drugs, high concentrations of three nucleoside analogs including ribavirin (half-maximal effective concentration (EC50) = 109.50 μM, half-cytotoxic concentration (CC50) > 400 μM, selectivity index (SI) > 3.65), penciclovir (EC50 = 95.96 μM, CC50 > 400 μM, SI > 4.17) and favipiravir (EC50 = 61.88 μM, CC50 > 400 μM, SI > 6.46) were required to reduce the viral infection (Fig. 1a and Supplementary information, Fig. S1). However, favipiravir has been shown to be 100% effective in protecting mice against Ebola virus challenge, although its EC50 value in Vero E6 cells was as high as 67 μM,4 suggesting further in vivo studies are recommended to evaluate this antiviral nucleoside. Nafamostat, a potent inhibitor of MERS-CoV, which prevents membrane fusion, was inhibitive against the 2019-nCoV infection (EC50 = 22.50 μM, CC50 > 100 μM, SI > 4.44). Nitazoxanide, a commercial antiprotozoal agent with an antiviral potential against a broad range of viruses including human and animal coronaviruses, inhibited the 2019-nCoV at a low-micromolar concentration (EC50 = 2.12 μM; CC50 > 35.53 μM; SI > 16.76). Further in vivo evaluation of this drug against 2019-nCoV infection is recommended. Notably, two compounds remdesivir (EC50 = 0.77 μM; CC50 > 100 μM; SI > 129.87) and chloroquine (EC50 = 1.13 μM; CC50 > 100 μM, SI > 88.50) potently blocked virus infection at low-micromolar concentration and showed high SI (Fig. 1a, b).

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Re: Are you a man, or a pouty little bitch? - [PEACE]
by Zenaan Harkness 10 Jan '21

10 Jan '21

The shuttening - "No Fap" website? It's a thing, for sure, and it's being targetted by the (((shut it downs))). Surprising. But also not surprising. Man, dats amazin'! >From the "I'll believe it when I see it" and the "snake no prisoners", sorry, I mean "take no prisoners" departments: The Porn Industry is Trying to Shut Down Anti-Masturbation “NoFap” Movement, Lawsuits Filed http://dstormer6em3i4km.onion/the-porn-industry-is-trying-to-shut-down-anti… NoFap “is a website and community forum that serves as a support group for those who wish to avoid pornography and masturbation.” https://www.nofap.com/ There’s also a Reddit community with the same name, where a post announces that “the porn industry and its friends” are trying to shut it down. https://www.reddit.com/r/NoFap/comments/duumhs/the_porn_industry_and_its_fr… The website has more details about what’s happening: https://nofap.com/defend-alex/ In retaliation for effectively whistleblowing the negative effects of compulsive Internet porn use, the porn industry and its allies are on a mission to defame, deplatform, and destroy NoFap and its founder Alexander Rhodes. … Alex has filed a lawsuit against the main orchestrator of defamation against him. For transparency’s sake to further prove the legitimacy, necessity, and authenticity of this crowdfunding campaign, the complaint is being provided in its entirety. https://www.pacermonitor.com/public/case/30620620/RHODES_v_PRAUSE_et_al Alexander Rhodes is the founder of NoFap. As a result of creating and operating this website, he has been targeted by an unprecedented campaign of defamation from entities who appear to be closely associated with the porn industry. Alex was forced to file a lawsuit to defend himself, as this defamation campaign is intended to destroy his reputation and distort public opinion about our website. Not only is this defamation destroying Alex’s quality of life and sleep, ultimately, we believe that this campaign is soon going to threaten our ability to continue keeping NoFap online. We need your help. ... From the lawsuit: https://nofap.com/wp-content/uploads/2019/11/Alexander-Rhodes-vs-Nicole-Pra… Defendant Prause also accuses NoFap of being a hate group, that NoFap promotes discrimination against protected groups, that NoFap advertises multiple antisemitic groups, and that by visiting NoFap people are supporting misogyny and antisemitism. The accusations against both Plaintiff Rhodes and NoFap will herein be referred to as the “False Statements”. ... 5 days muffas ... On Mon, Nov 11, 2019 at 10:17:35PM +1100, Zenaan Harkness wrote: > A 6 minute true story for y'all (and just a couple mentions o' God). > > tl;dr - "Am I a man . . . or a pouty little bitch?" > > Fell Back Into the Fallen State ... All For a Girl! ... > https://www.youtube.com/watch?v=FpWnAdhv3J8 > ~5:54 > > "I'm going to get myself out of this hole, because I put myself in > this hole." > > > JLP - "Rebuilding the family by rebuilding the man." > > > -- > 5 day challenge muffas :) > Do not wake the snake for 5 days.

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From the Assange indictment: Is there Extraterritoriality present in the Statutes the Indictment references?
by jim bell 04 Jan '21

04 Jan '21

From: https://www.justice.gov/opa/press-release/file/1153486/download 15(B) to intentionally access a computer, without authorization and exceeding authorizedaccess, to obtain information from a department and agency of the United States infurtherance of a criminal act in violation of the laws of the United States, that is, aviolation of Title 18, United States Code, Sections 641, 793(c), and 793(e).(In violation of Title 18, United States Code, Sections 371, 1030(a)(l), 1030(a)(2),1030(c)(2)(B)(ii).) [end of partial quote] There is a principle of American law, upheld by the Supreme Court, that a Federal law is only supposed to be considered of "extraterritorial" application (applies outside the boundaries of United States territory) if the Congress specifically intended that application, and was signified by including such language within the law itself.https://en.wikipedia.org/wiki/Extraterritorial_jurisdiction × "In Morrison v. National Australia Bank, 2010, the Supreme Court held that in interpreting a statute, the "presumption against extraterritoriality" is absolute unless the text of the statute explicitly says otherwise." "https://www.skadden.com/insights/publications/2016/06/us-supreme-court-cont… http://www.virginialawreview.org/volumes/content/rjr-nabisco-and-runaway-ca… >From that: "The Supreme Court threw out the lawsuit after invoking the presumption against extraterritoriality. That canon of statutory interpretation instructs judges to assume “that legislation of Congress, unless a contrary intent appears, is meant to apply only within the territorial jurisdiction of the United States.”[8] In applying the presumption in RJR Nabisco, however, a majority of four Justices[9] rejected multiple indications that Congress intended RICO’s private right of action to extend abroad[10] while raising the bar on what Congress must do to make its extraterritorial expectations clear.[11]" [end of quote] Understanding the presumption against extraterritoriality: https://scholarship.law.berkeley.edu/cgi/viewcontent.cgi?article=1170&conte… Very interesting: https://www.thefacultylounge.org/2019/04/some-thoughts-on-the-extradition-o… >From that:"THE RULE OF DUAL CRIMINALITY: Even if extradition is sought only under the computer intrusion indictment, it will still need to meet the test of dual criminality, found in Article 2, which provides that "An offense shall be an extraditable offense if the conduct on which the offense is based is punishable under the laws in both States." Although computer hacking is no doubt also a crime in the U.K., there is a further wrinkle of territoriality, because Assange's alleged offense was committed outside the United States. Another section of Article 2 provides:If the offense has been committed outside the territory of the Requesting State, extradition shall be granted in accordance with the provisions of the Treaty if the laws in the Requested State provide for the punishment of such conduct committed outside its territory in similar circumstances. If the laws in the Requested State do not provide for the punishment of such conduct committed outside of its territory in similar circumstances, the executive authority of the Requested State, in its discretion, may grant extradition provided that all other requirements of this Treaty are met." Unlike the U.S., however, Britain apparently takes a strict view of territorial jurisdiction. According to The New York Times, Britain has already denied a U.S. extradition request for computer intrusion, on the grounds that the offense was committed on British soil and would therefore have to be tried in the U.K. [end of quote] 18 U.S.C. 641 does not appear to explicitly have an extraterritoriality reference. https://www.law.cornell.edu/uscode/text/18/641 18 U.S.C. 793(c), nor the whole 793, does not appear to explicitly have an extraterritoriality reference. https://www.law.cornell.edu/uscode/text/18/793 × 18 U.S.C. 371 does not appear to explicitly have an extraterritoriality reference. https://www.law.cornell.edu/uscode/text/18/371 18 U.S.C. 1030 does not appear to explicitly have an extraterritoriality reference. https://www.law.cornell.edu/uscode/text/18/1030 Jim Bell

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Vaccine
by jim bell 01 Jan '21

01 Jan '21

Coronavirus vaccine still years away, experts warn https://www.yahoo.com/gma/health-experts-warn-life-saving-coronavirus-vacci…

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Moar Woar Poarn - Fw: Raqqa drift! Oh yeah :D
by Zig the N.g 17 Dec '20

17 Dec '20

Gets a little crazy on the roads o' Raqqa, muh stucco muffas :) How it truly went down: US0: "These fuckin' Syrians put a fuckin' country round our oil field - how DARE they!" US1: "Yeah, fuckin' sand niggers!" [Russkie's literally start to approach on highway, from behind.] RU0: "Ho, boys! Amerikanski oil "protectors" ahead. What do we?" RU1: "Ohoh! Drift this Tigr, baby - We's Baaaack!!" [serious literal military vehicle fast and furious ensues - see links below] [Russkies take first hummer, start hunting down second...] US0: "Muthufuckas! We got Russkies, lads, hang on tight!" [US2-4 happy they remembered "low frequency protection unit" adult diapers this morning.] RU0: "YEEEEE HAAAAAAW FIRETRUCKERRRRRRRRRRRRRRRRRRS!!!!" US1: [death gripping handle bar] "Oahhhh shiiiiit - why you driving offroaoad, buddy?!#!" US0: "Don't be a fuckin nigger! I think she'll make it - roadside don't look too fuckin rough." RU1: [grinning madly out side window at US hummer boys] "Baby, yeah! Lose you we will!" [to Ru0:] "SHIT! Watch locals, brutha!" [Russians narrowly miss a local who jumps out of the way] RU0: "May be lose them, but anuddah Oil thief pass we must!" RU1: "NO breaks, brutha! Do your copyright 'Boris Oil Thief Wedgy' manouver! Baby, yeah!" RU0: "Got it, brutha!" [hits accelerator hard, wedges all 3 vehicles as they come to screaming halt] [poetic license, not quite what actually happened, but part of upcoming movie script] US0: "HEY MUTHAFUCKAS WHAT THE FUCKIN FUCK ARE YA DOING!" US1: "FUUUUUUUUUUUUCK - Fucking PAPERWORK! FUCK YOU RUSSKIE!!" RU0: [cracks a 4L vodka bottle] "Here, drink have you, brutha!" RU1: [with huge cat eatin grin] "Awww, done cry little oil thief! Vodka take your paperwork away - HA HA HAAAA!" US0+1: "FUCK!!!" [See second 'tube below for Syrian villagers warmly welcoming American "democracy bringers" - with multiple gun shots :D] ----- Forwarded message from Zenaan Harkness <zen(a)freedbms.net> ----- Date: Thu, 20 Feb 2020 11:12:28 +1100 Subject: Raqqa drift! Oh yeah :D Enjoy ;) https://www.zerohedge.com/geopolitical/bizarre-road-rage-among-superpowers-… ----- End forwarded message -----

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[OT] [song] Patti Smith - People Have The Power
by Cecilia Tanaka 13 Dec '20

13 Dec '20

https://youtu.be/pPR-HyGj2d0 Patti Smith - People Have The Power I was dreaming in my dreaming Of an aspect bright and fair And my sleeping it was broken But my dream it lingered near In the form of shining valleys Where the pure air recognized And my senses newly opened I awakened to the cry That the people / have the power To redeem / the work of fools Upon the meek / the graces shower It's decreed / the people rule The people have the power The people have the power The people have the power The people have the power Vengeful aspects became suspect And bending low as if to hear And the armies ceased advancing Because the people had their ear And the shepherds and the soldiers Lay beneath the stars Exchanging visions And laying arms To waste / in the dust In the form of / shining valleys Where the pure air / recognized And my senses / newly opened I awakened / to the cry Refrain Where there were deserts I saw fountains Like cream the waters rise And we strolled there together With none to laugh or criticize And the leopard And the lamb Lay together truly bound I was hoping in my hoping To recall what I had found I was dreaming in my dreaming God knows / a purer view As I surrender to my sleeping I commit my dream to you Refrain The power to dream / to rule To wrestle the world from fools It's decreed the people rule It's decreed the people rule LISTEN I believe everything we dream Can come to pass through our union We can turn the world around We can turn the earth's revolution We have the power People have the power ...

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Julian Assange to be pardoned by Trump?
by CANNON 13 Dec '20

13 Dec '20

Rumor has it Trump is planning on pardoning Julian Assange, founder of whistleblower website Wikileaks.

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Kim Dotcom on Seth Rich's USB; USA: Whites not hate-filled enough for Dem program to succeed - [PEACE]
by Zenaan Harkness 10 Dec '20

10 Dec '20

** BREAKING: Kim Dotcom Tweets at Hannity: ‘Let's Talk About Seth Rich ... And Put an End to Russiagate’ https://russia-insider.us9.list-manage.com/track/click?u=fa2faf7034c3c3c413… ------------------------------------------------------------ by Michael Quinn Sat, Jan 26, 2019 Kim Dotcom, the infamous entrepreneur and political activist, wants to put an end to Russiagate. He has been talking about Wikileaks and Clinton since May 2015, which was a month before Donald Trump even announced his presidential campaign: Kim Dotcom: Julian Assange Will Be Hillary Clinton’s Worst Nightmare in 2016 ** Identity Stalinism: The Left's Incoherence Will Be Its Undoing https://russia-insider.us9.list-manage.com/track/click?u=fa2faf7034c3c3c413… ------------------------------------------------------------ by Steve Sailer Taki's Magazine Sat, Jan 26, 2019 The media’s latest Days of Rage, in which a white boy drove the national press into a frenzy by smiling at the leftist Person of Color banging a drum in his face, was like a greatest-hits collection of my old observations. So I’m going to take a victory lap to review how ideas I’ve been offering for years help explain much of the latest elite fury.

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Area51: S4 UFO AATIP Nimitz Fravor Lazar TTSA Physics Alien Tech
by grarpamp 08 Dec '20

08 Dec '20

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