December 2020 - cypherpunks - lists.cpunks.org

Martial Law - Cruel to be Kind [ PEACE! ] [ ENJOY! ]
by professor rat 22 Dec '20

22 Dec '20

Under martial law crime consists of not killing when the situation calls for it. Or not slowly crushing a mans testicles. A man named Zenaan perhaps. Zenaan Harkness could be with ISIS for all we know. I'm sure Eddie Gallagher could sort this out...given martial law, that is.

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Please review: Petition to President Trump to Declare Martial Law
by professor rat 21 Dec '20

21 Dec '20

Austrians have a right to interfere in US republican political-economy since possession is 9/10ths of the law. Since Jac Nassar, Rupert Murdoch, Julian Assmange and Pastor Craig we dominate the commanding heights of the US economy. So when we say your ass belongs to us we mean precisely that. Stop whining and bend-over.

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Grarpamps stabs self, jumps out of building
by professor rat 21 Dec '20

21 Dec '20

Clearly attempted suicide. And in related news... A German court has sentenced far-right extremist Stephan Batshit Balliet to life in jail for the murder of two people and the attempted murder of 50 others in a thwarted attack on a synagogue last year

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Batshit Crazy Palantir
by professor rat 21 Dec '20

21 Dec '20

Palantir paid Pando media. Yasha Levine worked for Pando media. Batshit crazy likes and respects Nazbol Turd, Yasha Levine. Pretty simple math. https://venturebeat.com/2020/12/19/covid-19-vaccine-distribution-algorithms…

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Cryptocurrency: Homomorphic / Privacy / Censorship / QSC / PQC / Quantum / AI
by professor rat 21 Dec '20

21 Dec '20

Post-quantum vulnerabilities assume quantum computers will be hostile to cryptoanarchy. The pessimist will assume all hope is lost and the optimist will look forward to the quantum blockchain. Gramps be like Chicken Little. "... however it may deserve respect for its usefulness and antiquity, [predicting the end of the world] has not been found agreeable to experience." -- Edward Gibbon, 'Decline and Fall of the Roman Empire'

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Quantum computing vices are now habits
by professor rat 21 Dec '20

21 Dec '20

18-19 years ago someone worried out loud about quantum decryption as a threat vector. I replied here that by the time it materialized we all have ubiqutous quantum-key-exchange. So it was an empty threat then and its an empty threat now - bit like " GovCorp ".

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Cryptocurrency: $24200 ATH Headlines
by grarpamp 20 Dec '20

20 Dec '20

FINALLY $20K!!! Bitcoin Right Now My proposal for the satish symbol, still looks like the old school 'S', it's quick and easy to write and it has 8 points representing 1 sat being in the eighth decimal place of 1 bitcoin Bitcoin Trading Need Karma to post on coinbase Someone transferred $165,000,000 in #bitcoin and paid a fee of 0.00006520BTC or about $1.20 One dollar and twenty cents. That's a transaction fee of 0.00000072% No 3rd party needed to facilitate this. Nobody could stop it. Nobody can reverse this. Potentially one of the biggest news stories in crypto history, Andrew Yang rumored to be named secretary of commerce BITCOIN HAS HIT A NEW ALL TIME HIGH! Bitcoin surpasses $20,000, setting another all-time high* !!!!! BITCOIN 19.000 $ AT THE MOMENT !!!! ITS TIME TO POST THIS AGAIN :) NEW ATH IS COMING !!!!! I made this for my boyfriend and he says he feels seen Bull Run // Beeple - artist Trump is reportedly considering pardon for Silk Road founder Ross Ulbricht Simple BTC price ticker with E Ink display I made this for 20K, but can't wait anymore :-) Bitcoin trying to hit that $20K like... Downvote me all you want but I'm selling Pornhub Might Have To Push Bitcoin Adoption After Mastercard and VISA Ban BTC IS BACK AT $19000, a few hundred from its ATH! I certainly didn't expect to see a headline like this from mainstream press. 24% of all existing dollars were printed in the last 12 months. So I took part in 14 airdrops reportedly worth '$2,827.90'.. We should adopt that S-thing we all used to draw in school as the symbol to denote Satoshis To the moon please HODL Bitcoin Bitcoin Is Now Accepted By All Pizza Hut Outlets In Venezuela Rohan Grey, advisor to the Democrat Congress Reps who put forth a new bill to ban stablecoins, is advocating to ban running blockchain nodes. We should demand that Stanford and the UN ICT agency sever all connections to him. What he is advocating is absolutely totalitarian and monstrously evil Well, if this isn't bloody bullish, then I don't know what is: The Queen of England is expressing an interest in blockchain. PayPal CEO Says Now Is the Time for Cryptocurrencies to Go Mainstream FOMO vs HODL Don't you love it how 19k has become so boring for us already? Each morning i wake up and see 19xxx i'm like meh... LoL.. This is the miracle of bitcoin; gets you greedy so quickly. your dreams became bigger, and it give you hope for the next day starting. Btw nothing is inside no need to click :) PayPal permanently banned my account due to CryptoCurrency buy/sells being treated as "item SALES" this thread is for others to be aware and to hopefully help all of us recover THIS IGNORANCE FUELED MISUNDERSTANDING Once bitcoin hits 100k, I'll open a museum featuring tweets of all the nocoiners hating it Face throwing a kiss 35% of all US dollars in existence have been printed in 10 months. Monday Art - Stoxart The probability of getting rich in six months is low, and the risk is high. The probability of getting rich in six years is high, and the risk is low(ish). Just want to say Congratulations to all the HODLers ETH2.0 Launched Wholesome FBI Eth2 Deposit Contract has reached 100% BTC smashes $23,000. Is at $23,500 now as I type. Bitcoin gave me hope Bitcoin users when the price drops before almost hitting 20k Bitcoin weekly summary... Its just toying with us... Pornhub says "Now Accepting Crypto Only" Coin holder since 2013 The final boss is approaching 40% of Americans don't have $400 in the bank for emergency expenses. I put many, many, many hours into the creation of this video... https://www.youtube.com/watch?v=Ai5z2T4WhWg Why Bitcoin Matters Why You Should Care Economical Ethical And Technological Perspective

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Cryptocurrency: Homomorphic / Privacy / Censorship / QSC / PQC / Quantum / AI
by grarpamp 20 Dec '20

20 Dec '20

> https://www.zdnet.com/google-amp/article/ibm-launches-experimental-homomorp… > https://techhq.com/2020/12/ibm-sets-out-to-crack-fhe-the-holy-grail-of-clou… https://en.wikipedia.org/wiki/Homomorphic_encryption https://en.wikipedia.org/wiki/Post-quantum_cryptography https://pqcrypto.org/ https://csrc.nist.gov/projects/post-quantum-cryptography https://openquantumsafe.org/liboqs/algorithms/ https://github.com/open-quantum-safe/liboqs https://github.com/ibm/fhe-toolkit-linux https://github.com/pqclean/pqclean https://www.ibm.com/security/services/homomorphic-encryption https://www.research.ibm.com/labs/uk/fhe.html https://medium.com/cryptoblog/what-is-lattice-based-cryptography-why-should… PQC already in sample applications for testing... zcash, openssl tls, curl, nginx, haproxy, ... Just as first generation coins are mostly going obsolete, those not considering integration of PQ safe, and strong cryptographic homomorphic and statistical privacy, into nextgen cryptos today, for the advances and users of 2030 2040 ... should expect their onchain value and privacy to be subject to such future risks. 99+% of all 4000+ cryptocurrencies today provide zero effective privacy, zero quantum resistance, and zero distribution against censorship. Worse than cash, gold, fiat, barter goods. That's pathetic.

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Chloroquine is "highly effective" at inhibiting reproduction of Novel Coronavirus nCov in cell culture.
by jim bell 20 Dec '20

20 Dec '20

https://www.dailymail.co.uk/health/article-8184997/Doctors-worldwide-say-ma… Doctors around the globe report that the malaria drug hydroxychloroquine seems the most effective treatment they've tried for coronavirus patients - but less than half as many doctors are prescribing it in the US as in other hard-hit countries like Spain. A survey of 6,200 doctors around the globe reveals that while few corners of the world are untouched by the virus, the pandemic is being handled very differently from country-to-country. And in some measures, the US continues to fall behind other nations' responses. For example, an American waits an average of four to five days to get results back after being tested for COVID-19. Half of doctors in Europe and most in China get the test results back within 24-hours. Dr Murali Doraiswamy, an adviser to Sermo, urged that countries should take note of what is working for doctors and governments elsewhere and move quickly to adopt practices that are saving lives. Hydroxychloroquine (pictured) was deemed the most effective coronavirus treatment comared to other options by more doctors worldwide than any other in a global survey =========================================================== On Sat, Feb 8, 2020 at 9:18 PM jim bell <jdb10987(a)yahoo.com> wrote: jim bell [chloroquine is an old-line drug typically used against malaria] [partial quote follows] https://www.asbmb.org/asbmb-today/science/020620/could-an-old-malaria-drug-… ASBMB Today Science Could an old malaria drug help fight the new coronavirus? Could an old malaria drug help fight the new coronavirus? By John Arnst February 06, 2020 Chloroquine might be getting new life as an antiviral treatment for the novel coronavirus that emerged in Wuhan, China in late 2019 and has infected some 25,000 people in more than 25 countries. For decades, the drug was a front-line treatment and prophylactic for malaria. In a three-page paper published Tuesday in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology write that both chloroquine and the antiviral remdesivir were, individually, “highly effective” at inhibiting replication of the novel coronavirus in cell culture. Their drug screen evaluated five other drugs that were not effective. The authors could not be reached for comment. Though the paper is brief, John Lednicky, a professor at the University of Florida’s Emerging Pathogens Institute, found its results intriguing. “It’s interesting in that it really lacks a lot of details but, nevertheless, if you look at the data as presented, at least in vitro, it seems like chloroquine can be used as an early-stage drug,” he said. “It would be very good if these types of experiments were repeated by more laboratories to see whether the same results occur across the board.” Chloroquine is a synthetic form of quinine, a compound found in the bark of cinchona trees native to Peru and used for centuries to treat malaria. Chloroquine was an essential element of mass drug administration campaigns to combat malaria throughout the second half of the 20th century, and remains one of the World Health Organization’s essential medicines. However, after the malaria parasites Plasmodium falciparum and Plasmodium vivax began exhibiting resistance to the drug in the 1960s and 1980s, respectively, it was replaced by similar antimalarial compounds and combination therapies. Chloroquine is still widely used against the three other species of plasmodium and to treat autoimmune disorders and some cases of amebiasis, an intestinal infection caused by the amoeba Entamoeba histolytica. Chloroquine’s antiviral properties were explored in the mid-1990s against HIV and in the following decade against severe acute respiratory syndrome, or SARS, which is closely related to the novel coronavirus. In 2004, researchers in Belgium found that chloroquine inhibited replication of SARS in cell culture. The following year, however, another team at Utah State University and the Chinese University of Hong Kong evaluated a gamut of compounds against SARS replication in mice infected with the virus, finding that chloroquine was only effective as an anti-inflammatory agent. They recommended that it could be used in combination with compounds that prevent replication. Nevertheless, in 2009, the Belgian group found that lethal infections of human coronavirus OC43, a relative of SARS, could be averted in newborn mice by administering chloroquine through the mother’s milk. [end of partial quote] Also: https://www.nature.com/articles/s41422-020-0282-0 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhengli Shi, Zhihong Hu, Wu Zhong & Gengfu Xiao Cell Research (2020)Cite this article 171k Accesses 1108 Altmetric Metrics details Dear Editor, In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood market in Wuhan.1 As of January 27, 2020, the Chinese authorities reported 2835 confirmed cases in mainland China, including 81 deaths. Additionally, 19 confirmed cases were identified in Hong Kong, Macao and Taiwan, and 39 imported cases were identified in Thailand, Japan, South Korea, United States, Vietnam, Singapore, Nepal, France, Australia and Canada. The pathogen was soon identified as a novel coronavirus (2019-nCoV), which is closely related to sever acute respiratory syndrome CoV (SARS-CoV).2 Currently, there is no specific treatment against the new virus. Therefore, identifying effective antiviral agents to combat the disease is urgently needed. An efficient approach to drug discovery is to test whether the existing antiviral drugs are effective in treating related viral infections. The 2019-nCoV belongs to Betacoronavirus which also contains SARS-CoV and Middle East respiratory syndrome CoV (MERS-CoV). Several drugs, such as ribavirin, interferon, lopinavir-ritonavir, corticosteroids, have been used in patients with SARS or MERS, although the efficacy of some drugs remains controversial.3 In this study, we evaluated the antiviral efficiency of five FAD-approved drugs including ribavirin, penciclovir, nitazoxanide, nafamostat, chloroquine and two well-known broad-spectrum antiviral drugs remdesivir (GS-5734) and favipiravir (T-705) against a clinical isolate of 2019-nCoV in vitro. Standard assays were carried out to measure the effects of these compounds on the cytotoxicity, virus yield and infection rates of 2019-nCoVs. Firstly, the cytotoxicity of the candidate compounds in Vero E6 cells (ATCC-1586) was determined by the CCK8 assay. Then, Vero E6 cells were infected with nCoV-2019BetaCoV/Wuhan/WIV04/20192 at a multiplicity of infection (MOI) of 0.05 in the presence of varying concentrations of the test drugs. DMSO was used in the controls. Efficacies were evaluated by quantification of viral copy numbers in the cell supernatant via quantitative real-time RT-PCR (qRT-PCR) and confirmed with visualization of virus nucleoprotein (NP) expression through immunofluorescence microscopy at 48 h post infection (p.i.) (cytopathic effect was not obvious at this time point of infection). Among the seven tested drugs, high concentrations of three nucleoside analogs including ribavirin (half-maximal effective concentration (EC50) = 109.50 μM, half-cytotoxic concentration (CC50) > 400 μM, selectivity index (SI) > 3.65), penciclovir (EC50 = 95.96 μM, CC50 > 400 μM, SI > 4.17) and favipiravir (EC50 = 61.88 μM, CC50 > 400 μM, SI > 6.46) were required to reduce the viral infection (Fig. 1a and Supplementary information, Fig. S1). However, favipiravir has been shown to be 100% effective in protecting mice against Ebola virus challenge, although its EC50 value in Vero E6 cells was as high as 67 μM,4 suggesting further in vivo studies are recommended to evaluate this antiviral nucleoside. Nafamostat, a potent inhibitor of MERS-CoV, which prevents membrane fusion, was inhibitive against the 2019-nCoV infection (EC50 = 22.50 μM, CC50 > 100 μM, SI > 4.44). Nitazoxanide, a commercial antiprotozoal agent with an antiviral potential against a broad range of viruses including human and animal coronaviruses, inhibited the 2019-nCoV at a low-micromolar concentration (EC50 = 2.12 μM; CC50 > 35.53 μM; SI > 16.76). Further in vivo evaluation of this drug against 2019-nCoV infection is recommended. Notably, two compounds remdesivir (EC50 = 0.77 μM; CC50 > 100 μM; SI > 129.87) and chloroquine (EC50 = 1.13 μM; CC50 > 100 μM, SI > 88.50) potently blocked virus infection at low-micromolar concentration and showed high SI (Fig. 1a, b).

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Assassination Politics needs to be edited down
by professor rat 20 Dec '20

20 Dec '20

Section nine could be tossed in its entirety. Its unoriginal and worse...boring. “Kropp on the other hand is a thinker. He proposes that a declaration of war should be a kind of popular festival with entrance-tickets and bands, like a bull fight. Then in the arena the ministers and generals of the two countries, dressed in bathing-drawers and armed with clubs, can have it out on themselves. Whoever survives the country wins. That would be much simpler and more than just this arrangement, where the wrong people do the fighting...” https://theanarchistlibrary.org/library/john-filiss-war-by-assassination

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