Science, Dec 1, 1995. "The Evolution of Molecular Computation." By Willem Stemmer. Comments on the limitations of Leonard Adleman's and Richard Lipton's DNA-computation research compared to the utility of sequence evolution computation. Although DNA sequencing of the selected solutions poses a practical problem for molecular computation, this drawback does not exist for computation with genetic algorithms or for in vitro evolution or computer simulations of natural evolution, called artificial life. Sequence evolution appears to be a useful general tool for solving many complex problems, whether the solution is a number, sequence, program, or structure. SEQ_uel (6 kb)