Coronavirus: Thread

grarpamp grarpamp at gmail.com
Wed Dec 1 20:19:48 PST 2021


> States See Looming Monoclonal Antibody Crunch As Biden Admin Rations Doses

Trump and other public figures received monoclonal antibodies.


Chinese Researchers Claim To Have Found Antibody 'Cure' For COVID

https://www.scribd.com/document/543871899/2021-11-29-470356v1-full

Have the Chinese been sitting on the secret cure for COVID this entire
time? One could be forgiven for harboring suspicions - especially now
that a team of Chinese researchers has purportedly found the human
antibody that helps the human body suppress the virus. This could lead
to a widely effective cure for COVID.

In the study, published Tuesday by researchers from Sun Yat-sen
University in Guangzhou, Zhejiang University in Hangzhou and a host of
other medical schools and institutes (all listed at the top of the
paper they published), the researchers explain how they used a
cryo-electron 50 microscopy (cryo-EM) to determine how human antibody
35B5 neutralizes SARS-CoV-2 by targeting a 51 unique epitope that
avoids the prevailing mutation sites on RBD identified not just in the
original "wild" strain of COVID (which initially emerged from Wuhan)
but also all the circulating VOCs. The researchers said this antibody
could be exploited to create a new vaccine that's more effective at
protecting against various strains of the virus.

Or perhaps even new antibody therapies that could offer even stronger
protection to the vulnerable than Merck' molnupiravir.

RT explained that "pan-neutralizing efficacy" means the antibody has
the capacity to suppress not just the original COVID, but also all the
existing variants and potentially even more variants that haven't yet
developed. Right now, it appears the antibody targets aspects of the
virus that haven't been impacted by the mutations.

These findings, the scientists argue, could be “exploited for the
rational design of a universal SARS-CoV-2 [Covid-19] vaccine.”

And while they haven't tested the antibody against the omicron
variant, the researchers said that the characteristics of the omicron
variant suggest it also has the characteristics that 35B5 requires to
suppress the virus.

RT posited that this breakthrough could become "pretty valuable" if
omicron does exhibit the ability to produce a surge in 'breakthrough'
infections, rendering the first generation of vaccines effectively
useless, something the CEO of Moderna appears eager to see.

Readers can find the full paper, which hasn't been peer reviewed, below:

2021.11.29.470356v1.full


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