what’s the problem with this idea? noninvasive cell-resolution brain imager (mistake) thereks already a brain activity imaging technology that uses infrared light actually we want to find the mistake. another similar idea rose ( we think the issue could be it takes too high-resolution of a camera / too long for thr person sitting there, maybe resolv 20240205 1642 -0800 we’ve thought about this and suspect it to work, but not certain. (more concerns rose, for example data on 1653 1654 ok. so the basic idea is: - a wavelength of light that can pass through the whole skull b 1655 1656 1744 this fresh paper uses x-rays in a really advanced-sounding way: Multi-resolution X-ray phase-contrast and dark-field tomography of human cerebellum https://opg.optica.org/boe/fulltext.cfm?uri=boe-15-1-142&id=544188
As the diameter of thin axons(~ 1 micrometer) is very close to the resolution limit of the HR phase-contrast images, their segmentation was not possible
But it sounds like they were possibly able to count and measure individual cells, kind of. image from paper attached. this was just the first paper i found and i have a lot of understanding to do. i’m curious about the micrometer wavelength of light region. i wonder if the brain structure were modeled with a wonky new transformer that the analysis could significantly simplify: it would for example then be much much easier to integrate different modes of observation. this could be trained on nonliving (or nonhuman :/) tissue via microscopic images of cross-sections after noninvasive measurement. i bet there are more cool papers out there showing cellular-level living bioimaging (of the brain).
