One problem with operating a nym is that people almost always respond to it with suspicion and hostility, even on this list. It would be nice to have an ordinary looking e-mail address that took in messages, encrypted them for your public key, and then sent them out to alt.anonymous.messages for pickup. Going the other way it would be nice if the account would accept signed messages and send them out as normal e-mail or news articles. This would allow nyms to participate in NetWorld like everyone else.
Note that this does not require one to trust the operator of the machine - all they have is a public key and no information of your identity. This should be easy to set up.
That is what nym servers (denoted as "alpha" and "newnym" in the remailer lists) do. See http://anon.efga.org/anon for more information.